4 edition of Apoptosis found in the catalog.
Includes bibliographical references and index.
|Statement||edited by George P. Studzinski.|
|Series||The practical approach series -- 216|
|Contributions||Studzinski, George P.|
|LC Classifications||QH671 .A6526 1999|
|The Physical Object|
|Pagination||xxii, 244 p. :|
|Number of Pages||244|
|ISBN 10||0199637857, 0199637849|
|LC Control Number||99033468|
Apoptosis, or programmed cell death, is a natural process by which damaged or unwanted cells are dismantled in an orderly and atraumatic fashion. It is of critical importance in development, homeostasis, and cell population control. Research over the last decade is now enabling scientists to comprehend how genes and the protein products interact to control apoptosis. Apoptosis is an intrinsic cell‐suicide programme, which ensures tissue homeostasis and safeguards the organism by eliminating unnecessary and unwanted cells, or cells that may constitute some form of danger to the organism, for example, tumour erum-c.com by: 2.
Many diseases and disorders are linked with the life and death of cells -- increased apoptosis is a characteristic of AIDS, Alzheimer's and Parkinson's disease, while decreased apoptosis can signal lupus or cancer. Understanding how to regulate apoptosis could be the first step to treating these erum-c.com: Molly Edmonds. Introduction to Apoptosis 2. Cellular Events of Apoptosis 3. Mechanism 4. Importance. Introduction to Apoptosis: Every normal living cell of animals, plants and even bacteria are mortal. I.e., they must die after some time. Cell death is a finely tuned programme inherent in the cells genetic machinery.
Apoptosis in Pathologic Conditions • DNA damage due to radiation, chemotherapy. • Accumulation of misfolded proteins leads to ER stress which ends with apoptosis. • Cell death in viral infections that induce apoptosis such as HIV and Adenovirus or by the host immune response such as hepatitis. • Organ atrophy after duct obstruction. Apoptosis is a unique morphological pattern of cell death which is coordinated by tightly regulated signaling pathways within dying cell. This highly regulated modality of cell death occurs in such a way that the dying cell's contents is neatly packaged into small packets which are rapidly taken up and degraded by local macrophages without the induction of inflammation.
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The cells of a multicellular organism are members of a highly organized community. The number of cells in this community is tightly regulated—not simply by controlling the rate of cell division, but also by controlling the rate of cell death.
If cells are no longer needed, they commit suicide by activating an intracellular death program. This process is therefore called programmed cell death Cited by: Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy: New Perspectives and Opportunities (Advances in Experimental Medicine and Biology Book ) by Christopher D.
Gregory. Kindle $ $ 69 $ $ Hardcover More Buying Choices $ (14 used & new offers). This book describes in simple terms the philosophical and technical difficulties in defining the moment of death for a cell, and discusses the biological implications and significance of apoptosis.
The book is written for advanced undergraduate and postgraduate students, and Cited by: Cambridge Core - Molecular Biology, Biochemistry, and Structural Biology - Apoptosis - by Douglas R.
Green / edited by John C. ReedCited by: This book looks at the latest research studies on apoptosis in medicine. Apoptosis book is divided into three sections for convenient and easy reading. The first section which comprises two chapters is an introduction of the subject of apoptosis to the uninitiated.
The second section which comprises a single solitary chapter looks at apoptosis in normal physiology during bone resorption under mechanical Author: Tobias M. Ntuli. The significance of apoptosis The development and maintenance of multicellular biological systems depends on a sophisticated interplay between the cells forming the organism, it sometimes even seems to involve an altruistic behaviour of individual cells in favour of the organism as a whole.
During development many cells are. Click on the title to browse this book. Apoptosis. This is the currently selected item. Sort by: Top Voted. Apoptosis. Biology is brought to you with support from the Amgen Foundation.
Biology is brought to you with support from the. Our mission is to provide a free, world-class education to anyone, anywhere. Apoptosis (from Ancient Greek ἀπόπτωσις "falling off") is a form of programmed cell death that occurs in multicellular organisms.
Biochemical events lead to characteristic cell changes and erum-c.com changes include blebbing, cell shrinkage, nuclear fragmentation, chromatin condensation, chromosomal DNA fragmentation, and global [vague] mRNA erum-c.com: D Apoptosis is a type of programmed cell death in which molecules signal for the initiation and execution of cell death in response to certain regulatory or stress-induced signals.
The regulation of apoptosis is critical to the proper development and function of organisms. Abstract. The historical development of the cell death concept is reviewed, with special attention to the origin of the terms necrosis, coagulation necrosis, autolysis, physiological cell death, programmed cell death, chromatolysis (the first name of apoptosis in ), karyorhexis, karyolysis, and cell suicide, of which there are three forms: by lysosomes, by free radicals, and by a genetic Cited by: May 30, · Apoptosis provides a current and comprehensive collection of methods for the study of cell death.
Using a diverse range of technical approaches and model systems, the chapters in this volume cover topics from the cellular and organismal to the molecular and erum-c.com Edition: 1.
Cell Death. Autophagy, Apoptosis and Necrosis. This book is a collection of selected and relevant research, concerning the developments within the Cell Death field of study.
Each contribution comes as a separate chapter complete in itself but directly related to the books topics and objectives. The target audience comprises scholars and Cited by: 3. Bok (Bcl-2 related ovarian killer) is a protein-coding gene of the Bcl-2 family that is found in many invertebrates and vertebrates.
It induces apoptosis, a special type of cell erum-c.comtly, the precise function of Bok in this process is erum-c.coms: BOK, BCL2L9, BOKL, BCL2-related ovarian. Mitochondrial apoptosis inducing factor protein is a caspase-independent death effector that cause nuclei to undergo apoptotic changes.
The apoptosis process begins when the mitochondria releases apoptosis inducing factor. The apoptosis inducing factor then leaves through the mitochondrial membrane and enters the cytosol.
“The book ‘Essentials of Apoptosis’ is a collection of 31 review articles, covering a wide variety of approaches in studying cell death. It enables the reader to get acquainted with many aspects of apoptosis, and impressive amounts of references cited in each of.
Apoptosis, in biology, a mechanism that allows cells to self-destruct when stimulated by the appropriate trigger. Apoptosis can be triggered by mild cellular injury and by various factors internal or external to the cell; the damaged cells are then disposed of in an orderly fashion.
As a. Apoptosis definition is - a genetically directed process of cell self-destruction that is marked by the fragmentation of nuclear DNA, is activated either by the presence of a stimulus or removal of a suppressing agent or stimulus, is a normal physiological process eliminating DNA-damaged, superfluous, or unwanted cells, and when halted (as by gene mutation) may result in uncontrolled cell.
Oct 18, · This 3D medical animation explains the functioning of the extrinsic and intrinsic apoptotic pathways. We start off by taking a look at the important role. The book is written primarily for basic science and clinical researchers (graduate students, postdoctoral fellows, scientists).
Biomedical researchers working in radiation biology, pharmacology, and molecular pathology also will value this book because of its focus on. The ability to detect and quantify apoptosis, to understand its biochemistry, and to identify its regulatory genes and proteins is crucial to biomedical research.
In Apoptosis: Methods and Protocols, Second Edition, expert researchers describe the techniques to best investigate the critical steps involved in the apoptotic process. Presented.Novus-lu Apoptosis Handbook. Apoptosis is derived from the Greek prefix apo- meaning “away, off”, and the word ptosis, meaning “falling, a fall”.
Apoptosis, a form of programmed cell death, is a coordinated and step-wise series of biochemical reactions resulting in the.apoptosis and necrosis—can contribute to hepatocyte death. In apoptosis, the affected cell actively participates in the cell death process, whereas in necrosis the cell death occurs in response to adverse conditions in the cell’s environment.
Numerous factors that may con .